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Also, according to an older study from 2000, the compound hydrangenol an allergen in hydrangeas may cause allergic reactions when hydrangea root comes in direct contact with the skin ( Lastly, due to the lack of information regarding the toxicity of the root, people who are pregnant or breastfeeding should avoid its use

A., Prez-Martos, A., Montoya, J

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The discovery of new lipolytic enzymes and coregulators, the demonstration that lipophagy and lysosomal lipolysis contribute to the degradation of cellular lipid stores and the characterization of numerous factors and signalling pathways that regulate lipid hydrolysis on transcriptional and post-transcriptional levels have revolutionized our understanding of lipolysis