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It is also reported to be closely involved in the pathology of multiple sclerosis and other inflammatory diseases in the CNS [237]
During these life stages, hyperinsulinemia is considered as part of the physiological responses against reduced insulin sensitivity elicited by growth hormones 85,86,87
Similar results were observed in APP23 mice on a high-fat diet ( 42 clearance but did not inhibit APP processing (Riddell et al., 2007)
Ying WZ, Wang PX, Aaron KJ, Basnayake K, Sanders PW
