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[27] found that overexpression of the most abundant GPX, GPX-1, served a protective role from platelet hyperactivity and age-dependent increased susceptibility to venous thrombosis after inferior vena cava ligation in murine models

Pregnancy and Breastfeeding: There is currently not enough clinical research to confirm the safety of high-dose glutathione supplementation during pregnancy or while nursing

Functional significance of the ThDP-dependent enzyme isoforms, which are the enzyme variants arising from alternative splicing of transcripts from a single gene, or through post-translational modifications, is studied even less than that of isoenzymes

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