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Description
Nrf2 binds to antioxidant response elements (AREs) to enhance the expression of proteins essential for maintaining cellular redox balance [240, 241]
Lung disease in a global context
Intrinsic disorders can be divided into abnormalities of the RBC membrane, metabolic enzymes, or hemoglobin
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The different hGSTP1-1 mutants show slightly altered regioselectivities in the formation of the individual GSH conjugates of clozapine which suggests that the binding orientation of the reactive nitrenium ion of clozapine is affected by the mutations [34]
