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Environmental agents including air pollutants and airway infection are the major trigger of exacerbations

Curcuminoids are composed of three primary constituents: curcumin (60%70%), demethoxycurcumin (DMC) (20%27%), and bisdemethoxycurcumin (BDMC) (10%15%), along with other secondary metabolites of lesser clinical significance (Figure 1) (Priyadarsini, 2014)

Mechanisms of outer membrane vesicle entry into host cells