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By month 34, most patients tolerate semaglutide well, with only occasional flares related to specific meals or stress

Some 52 subjects (54.2%) reached the maximum recommended dose of the drug

Contact your doctor as soon as you can if you notice these symptoms while taking Ozempic for weight loss or diabetes treatment, or while taking Wegovy or another weight-loss medication

A SURMOUNT-1 post-hoc analysis of 2,542 women, published in Obesity in 2025, found perimenopausal women on tirzepatide lost 23% of body weight against 3% on placebo, almost identical to the premenopausal result