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R.AlnaimiA
Transcription factors such as PPAR (peroxisome proliferator-activated receptor alpha) and C/EBP (CCAAT/enhancer-binding protein alpha) are key regulators of MCAD expression
Abstract To develop an LCMS/MS method for simultaneous quantification of mildronate and L-carnitine, and to investigate the pharmacokinetic profile of mildronate in rats, its effect on L-carnitine homeostasis, as well as the exposure characteristics, underlying mechanisms, and their associations with therapeutic efficacy and toxicity risks
