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Prior to metabolism in the mitochondria, the acetyl group is transferred to coenzyme A (CoA) to form acetyl-CoA, which enters the TCA cycle to generate ATP through oxidative phosphorylation
For instance, a study shows that after topical application of L-carnitine alone, the concentration in the local tissue is only 1/10 to 1/5 of that after oral administration, and it cannot significantly increase the proportion of fatty acid oxidation
10, 2022, pp
Effect of vitamin D3 on self-perceived fatigue: A double-blind randomized placebo-controlled trial
