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Hypoglycemic medicines in the treatment of Alzheimers disease: Pathophysiological links between AD and glucose metabolism

Moreover, loss-of-function mutations of succinate dehydrogenase (SDH) increase cellular succinate level, which inhibits DNA demethylation and contribute to tumorigenesis [62,63]

[128] did not report benefits of folate supplementation in patients with SZ with prominent negative symptoms, but did report a significant interaction between treatment and MTHFR genotype

Thus, regular consumption of cruciferous vegetables can potentially contribute to the formation of more significant concentrations of SFN