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It is not a drug, dietary supplement, or product intended for human or animal consumption.
The National Resource Center for Nutrition and Aging confirms there is no set upper-level limit for vitamin B12 dosage

Zonisamide is an antiepileptic drug that has serotonergic and dopaminergic activity in addition to its ability to act as a blockade of sodium and calcium channels

For others, it may take 23 days, especially if they were significantly deficient