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doi: 10.1038/sj.embor.7400667
FXR-deficient mice are resistant to obesity induced by a high-fat diet, and transferring their microbiota to germ-free wild-type mice reduces obesity and improves glucose tolerance, indicating that the gut microbiota promotes weight gain and hepatic steatosis in an FXR-dependent manner (Parsus et al., 2017)
[DOI] [PubMed] [Google Scholar] 9.Feinman R.D., Pogozelski W.K., Astrup A., Bernstein R.K., Fine E.J., Westman E.C., Accurso A., Frassetto L., Gower B.A., McFarlane S.I., et al
Sympathetic neural mechanisms in obstructive sleep apnea
