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While the classic model of GI neuronal mechanosensitivity attributes this property to IPANs, where distortion of their cell bodies or processes triggered action potential discharge [95, 96], there is increasing evidence that a broader population of enteric neurons, that is, including S-type neurons, also display mechanosensitive properties [46, 47, 63] and these have been termed more generally mechanosensitive enteric neurons (MEN) [97]

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For those needing immediate and effective results, methylcobalamins direct bioavailability makes it the more efficient choice