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CXCL-8 as a signature of severe helicobacter pylori infection and a stimulator of stomach region-dependent immune response

doi: 10.1158/0008-5472.CAN-12-3386

An experimental treatment can essentially reverse type 1 diabetes in certain types of laboratory mice
Hyperglycemia-induced interactions between AGEs and their receptor, receptor for advanced glycation end products (RAGE), activate NF-B signaling in renal macrophages, thereby amplifying pro-inflammatory cytokines and chemokines that recruit monocytes to the kidney
