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While ethanol metabolism in the gastrointestinal tract locally generates low levels of acetaldehyde and other toxic metabolites, the liver is the primary organ that carries out ethanol metabolism and consequently sustains the greatest organ damage from heavy drinking (41, 42)

[DOI] [PMC free article] [PubMed] [Google Scholar] 243.Schrauwen P

144 Similarly, Pien Tze Huang, a traditional Chinese medicine, also exhibits protective effects against APAP-induced liver injury by significantly reducing levels of NLRP3 inflammasomes and proinflammatory cytokines

188 Moreover, flexibility and mobility exercises should not be overlooked