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At the start of the test, the speed was set at 8 km/h, and after one hour, it was increased every three minutes by 1 km/h with one minute of rest before every heart rate increment to exhaustion

doi: 10.1074/jbc.M117.791202

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Activated microglia impairs neuroglial interaction by opening Cx43 hemichannels in hippocampal astrocytes