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Research in 2022 concluded that high B12 in cancer patients is often an epiphenomenon

Combined with the structural changes to the Purkinje cells [179, 180], possible Purkinje cell loss [181], Purkinje cell axonal alterations, and/or abnormal Purkinje cell synaptic organization [182, 183] reported in postmortem human ET tissue, the VIM neurons are likely entrained by abnormal cerebellar activity
One compound reduces energy intake, the other increases energy expenditure at the mitochondrial level

10.1002/dvdy.22350 235 RisbudM
