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In addition to maintain the cellular redox balance, the catalytic cycle of methionine residues modulates the signal transduction pathways by the protein post-translational modifications, analogous to phosphorylation and dephosphorylation cycles (53, 54)

The Haybittle-Peto procedure for generating early stopping boundaries will be used (43)

For instance, SAP-induced MMP-9 activation accelerates glycocalyx degradation, thereby directly linking pancreatic inflammation to systemic microcirculatory collapse [18]

Varadharajan V, Rajendran R, Muthuramalingam P et al (2025) Multi-omics approaches against abiotic and biotic stressa review