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In summary, immunometabolic crosstalk is a pivotal feature of OA progression and a critical component of ferroptosis regulation
The primary function of IDH1 and IDH2 is to serve as producers of NADPH to enhance the cellular responses to oxidative stress and the generation of reactive oxygen species, ROS
This disease is in a relatively privileged position when it comes to clinical trials: it can benefit from special regulations while having studies with sufficient sample size to have more powerful, reliable, and replicable results
Triethanolamine (TEAM) was used as a base
