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Description
When the transport of dopamine into synaptic vesicles is obstructed or VMAT2 is inhibited by drugs such as tetrabenazine and reserpine, excessive dopamine can accumulate in the cytoplasm, leading to the auto-oxidation of dopamine and the formation of harmful by-products, eventually leading to neurodegeneration
ESI injections are temporary and may last from a couple of weeks to a couple of months
As progress is made, the frequency might be adjusted to bi-weekly or monthly to maintain consistent energy levels and support ongoing metabolic function

