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As people reach old age (above 70), there appears to be an increase in incidence of relative carnitine deficiency [5]

Plasmonic materials, particularly noble metals, exhibit unique surface resonances under laser irradiation, making them ideal matrix materials because of their high thermal carrier yield and porous structure, which effectively enhance the desorption and ionization capabilities of analytes

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Furthermore, alternative routes are possible for generating Esterbauer's dioxetane intermediates (vide infra)