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A latest study has shown that the overexpression of the LA synthase gene (Lias) significantly attenuated oxidative stress (Tfam) and histological steatosis in the livers of db/dbC57BL/6 mice fed a normal diet [87]

In general, phase I metabolizing enzymes catalyze reactions that increase the reactivity of hydrophobic (fat-soluble) compounds, preparing them for reactions catalyzed by phase II biotransformation enzymes

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Studies show that limiting alcohol intake helps maintain stable homocysteine levels and supports glutathione production
