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When long-term adverse conditions occur, such as drought, salt stress, temperature shifts, predation, or nutrient limitation, damaging levels of ROS can accumulate either directly, or because of the metabolic shifts required for acclimation (Ensminger et al
4-PBA group (rats were injected intraperitoneally with MTX on day 7 plus 4-PBA (150 mg/kg) by intraperitoneal injection every other day (days 2, 4, 6, 8, and 10) (Soliman et al., 2019)
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Chronic disease and self-injection: ethnographic investigations into the patient experience during treatment
