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2016 Feb 23

Mutant forms of SOD1, an antioxidant enzyme that catalyzes the conversion of O 2 - to H 2 O 2 and O 2 , which is critical in OS regulation [32, 33], have been associated with loss of oxidative control and excessive production of ROS [34-36]

Furthermore, Nikolaidis et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 327.Lscher W, Potschka H, Sisodiya SM, Vezzani A
