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These free radicals are natural byproducts of your increased oxygen consumption and energy production

References: Radenkovic D, Reason S, Verdin E

Mutations in SOD1 can cause familial ALS (several pieces of evidence also show that wild-type SOD1, under conditions of cellular stress, is implicated in a significant fraction of sporadic ALS cases, which represent 90% of ALS patients.), [58] by a mechanism that is presently not understood, but not due to loss of enzymatic activity or a decrease in the conformational stability of the SOD1 protein

10.1016/j.chembiol.2018.01.011 23 FariaM.PratsE.Gmez-CanelaC.HsuC
