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glutathione reductase ascorbate Glutathione-ascorbate cycle Glutathione biosynthesis pathway and glutathione-ascorbate
Description
Nwose et al
Cancer cells overexpressing xCT present an overactivation of the glucose-dependent PPP, as a mean of replacing NADPH consumed in the imperative conversion of cystine into cysteine (111) and by signaling pathways activated by oxidative stress, including PI3K/AKT/mTOR (112, 113) and MAPK pathways (110)
Bone morphogenetic protein signaling is impaired in a HFE knockout mouse model of hemochromatosis
H.MaronL
