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10.3389/fonc.2023.1089115 122

[PubMed] [Google Scholar] 128.Ranjan A, Ramachandran S, Gupta N, Kaushik I, Wright S, Srivastava S, et al

However, its successful application will require further elucidation of TREM biology in humans, regarding the cell-type specificity of TREM expression (e.g., in astrocytes, oligodendrocytes, and neurons), species differences between humans and mice, immature metabolic and mitochondrial features of in vitro culture (e.g., BV and iPSC-derived cells), early-onset or late-onset, and the temporal dynamics of disease progression with senescence

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