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Krishan, S

Elderly male subjects had the highest observed mean increase, approximately 2.4 fold (198.3 ng.hr/mL, range 155.6-255.3 versus 83.2 ng.hr/mL, range 41.1-142.5 for younger males) while levels in elderly females were increased to a much lesser extent, approximately 1.2 fold (143.8 ng.hr/mL, range 96.1-196.3 versus 115.9 ng.hr/mL, range 36.1-182.9 for younger females)

Additionally, NAC reduced apoptotic signaling (including cytochrome c release and caspases 3/9) and neuroinflammation (as indicated by CD11b expression)

doi: 10.1371/journal.pone.0057495 324 Marshall-GradisnikSHuthTChackoAJohnstonSSmithPStainesD