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Description
Colchicine is not safe in patients with substantial kidney or liver disease and should not be used along with drugs such as ketoconazole (eg, Nozoral), fluconazole (Diflucan), clarithromycin (Biaxin, an antibiotic), cyclosporine (eg, Sandimmune, an immunosuppressant agent), or ritonavir (Norvir, an antiviral drug) due to the potential for drug-drug interactions

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In such cases, your doctor might even prescribe B12 injections for you to take at home, with the frequency depending on your individual needs
