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(3) metabolic reprogramming, involving ANT dysfunction (impairing ATP/ADP exchange in ischemic heart disease) and SLC25A20 downregulation (reducing fatty acid oxidation in cardiomyopathies)

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Osteoporosis Osteoporosis is an age-related bone disease characterized by reduced bone mass and alterations in bone microstructure, leading to increased fragility and a greater risk of fractures, particularly among elderly individuals