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Thus, GSH increase seems to promote tumour growth

Purification and characterization of a carboxylesterase involved in malathion-specific resistance from Tribolium castaneum (Coleoptera: Tenebrionidae)

doi: 10.1038/ng.3421

Furthermore, increased copper levels can increase reactive oxygen species (ROS) production and activate the NF-B signalling pathway, exacerbating inflammatory changes within the vascular wall and promoting atherosclerosis (25)
