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Whilst insulin promotes glucose uptake for ATP synthesis, IGF-1 binds to plasma membrane proteins promoting amino acid uptake and usage of this energy in protein synthesis

doi: 10.1073/pnas.86.12.4695

Gambogic acid induces GSDME dependent pyroptotic signaling pathway via ROS/P53/Mitochondria/Caspase-3 in ovarian cancer cells

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