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Description
SIRT5 regulates the NRF2/HO-1 pathway in a ROS-dependent manner to inhibit cisplatin (CDDP)-induced DNA damage, thereby promoting CDDP resistance in ovarian cancer (OC) [77]

Foods rich in sulfur can help support glutathione production

CSF studies sometimes show oligoclonal bands [19,20,21,22]

Additionally, compounds such as PL 1-3 (Li et al., 2023) and Empagliflozin (Long et al., 2024) have garnered attention for their ability to upregulate SIRT1, enhance mitochondrial function, and reduce oxidative stress and senescence markers, thereby mitigating the progression of liver diseases such as MASLD