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Clinical studies specifically monitoring glucose metabolism through oral glucose tolerance tests found no significant changes in glucose handling, and fasting insulin levels remained stable throughout treatment periods lasting up to 24 weeks

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The presentation of the brain and peripheral vessels (superior mesenteric vein, portal vein, inferior caval vein, azygos vein, and abdominal aorta) was recorded in deeply anesthetized rats, with a camera attached to a VMS-004 Discovery Deluxe USB microscope (Veho, United States) (Gojkovic et al., 2021a