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In addition to our literature review, an animal model study has shown that amlodipine inhibits AGEs deposition in the inner membrane of the aorta, despite the absence of a statin effect on plasma lipids 97
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Microglia, the primary immune cells of the central nervous system, are deeply affected by signals originating from the gut microbiota, including microbial metabolites like short-chain fatty acids (SCFAs) and endotoxins such as lipopolysaccharides (LPS)

Their multiple activities, including proliferation, differentiation, and ultimately cell death, are essential for ontogeny, homeostasis, and disease progression [1]
