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It was shown to stimulate the proliferative capacity of epithelial cells (Khavinson et al 2003a, b) and fibroblast (Linkova et al 2016) in vitro thereby increasing the lifespan of the cells

SAM is involved in hundreds of methylation reactions throughout the body, and the systemic effects of preserving SAM through NNMT inhibition in tissues beyond adipose tissue remain unknown

Understanding these potential factors can help address sleep issues more effectively
