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Our clinical staff is trained to monitor patients closely during and after the procedure for any signs of an adverse reaction

Buffered NAD+ ships with a pH stabilizer (most commonly Tris) that brings the reconstituted solution closer to physiological pH (~7-8.5), while unbuffered NAD+ reconstitutes acidic (~pH 3-4) and is more often associated with injection-site stinging

It is most common in the weight-bearing joints like the hips and knees, but can also occur in the shoulders or other smaller joints