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doi: 10.1158/2326-6066.Cir-17-0479 25 GongLLiGYiXHanQWuQYingFet al

Knig, Phytochemistry 1996 , 44 , 471-474

Since then, its activation has been well documented to be a crucial mechanism for stress response in the nervous system, where its constitutive levels are quite low, but it can be highly induced [37,83]

Most individuals begin to see more substantial results after three to six months of consistent therapy
