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Besides a high expression, also a high activity of Pgp determines doxorubicin resistance

( 10.1093/humrep/dew284) [DOI] [PMC free article] [PubMed] [Google Scholar] Reuter SE, Evans AM.2012

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Researchers working with the peptide storage guide for melanocortin compounds should avoid repeated freeze-thaw cycles, as these can degrade peptide structure and reduce biological activity
