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It has been shown that resistance of AML stem cells to ven / aza occurs through the up-regulation of FAO, which occurs by a mechanism related to mutations in the RAS pathway genes [135]
doi: 10.1074/jbc.M109.070201 301 WichA.TarczewskaA.OyharA.OrowskiM
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Strom BL, Schinnar R, Apter AJ, Margolis DJ, Lautenbach E, Hennessy SCE, et al
