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designed a duallocked PMB based on the parallel logic gate, using a DSBDPbased photosensitizer and a BHQ3, linked by two enzymesensitive peptides (PLGVR for MMP2 and GFLG for cathepsin B) (Figure 7a)

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The novel point was the rapid activation of the collateral rescuing pathways (i.e., activation of the azygos veins direct blood flow delivery) to reestablish the reorganized blood flow [4,10]