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Animal studies have provided evidence that sitagliptin and linagliptin exhibit the ability to attenuate the activity of NLRP3/inflammasome (198)

study, remodeling and proliferation markers such as matrix metalloproteinases (MMP2 and MMP9) and proliferating cell nuclear antigen (PCNA) increased following the increase in the expression of PPAR ( The effect of butyrate on lipogenesis and lipolysis is contradictory and seems to be due to differences in the dose, duration of butyrate treatment, and cell phenotype in the in vitro studies

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