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Additionally, priming of PMNs by TNF- induces p38 mitogen-activated protein kinase (MAPK)-dependent phosphorylation of p67 phox (Brown et al., 2004), which causes conformational changes in p67 phox , allowing it to interact with gp91 phox (Dang et al., 2006

[DOI] [PMC free article] [PubMed] [Google Scholar] 278.Schndorf, D

Afterward, cell phenotype was examined by testing their senescence level and cartilage formation capacity
