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N Engl J Med 348: 25992608, 2003

Supplement Facts: Serving Size: 4 capsules Servings Per Container: 90 Amount Per Serving: Creatine Monohydrate: 3000 mg *RI - Reference Intake Ingredients: Creatine Monohydrate, HPMC (Vegetarian Capsule Shell)

EnergyMetabolism & Cellular Health: L-Carnitine L-Tartrate is crucial for transporting fattyacids into mitochondria for energy production, while CoQ10 is essential for ATPsynthesis (cellular energy currency)

A 2014 systematic review and meta-analysis of 31 randomized controlled trials in a total of 1,734 patients with ESRD found that L-carnitine treatment administered either orally or intravenously resulted in reductions of serum C-reactive protein (a marker of inflammation and predictor of mortality in patients undergoing hemodialysis) and LDL-cholesterol, although the latter was not deemed to be clinically relevant (73)