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However, the combination of vitamins B1, B6, and B12 demonstrated a superior effect to treatment with only vitamin B12 in regard to synapsing, which was statistically significant regardless of whether cells were insulted or not
However, insulin is not an ideal drug to be developed as a major treatment for PD due to insulin desensitization

PLoS One 6 , e22623 (2011)

doi: 10.3748/wjg.v10.i16.2379