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Patients on selective serotonin reuptake inhibitors (SSRIs) or tricyclic antidepressants need closer monitoring if phentermine is used, as serotonin syndrome, though rare, is a medical emergency

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One such compound, chrysophanol, extracted from Rheum palmatum , has been shown to improve memory, learning, and social interaction in ASD mice through the downregulation of the mTOR pathway [133]

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