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The mechanism of action remains to be elucidated and may not be related to antioxidant activity (Lyseng-Williamson and Perry, 2003)

This insight suggests that methionine restriction (MR) may effectively replicate some of the beneficial metabolic effects associated with caloric restriction (CR)

Therefore, further translational studies are necessary to enhance luteolins bioavailability, optimize dosing strategies, and create new drug delivery systems to improve its efficacy