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10.1001/jama.281.15.1415 JAMA

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In patients over two years of age who are clinically suspected of having a hereditary mitochondrial disease, Depakote Sprinkle Capsules should only be used after other anticonvulsants have failed

Avoid if you have: Kidney disease : Reduced clearance may cause accumulation Seizure disorders : May increase seizure frequency Hypothyroidism : May interfere with thyroid hormone Consult healthcare provider before starting if you have chronic conditions or take medications
