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Li Y, Guan Y, Wang Y, Yu CL, Zhai FG, Guan LX

Yang Y, Tian Q, Wu S, Li Y, Yang K, Yan Y, et al

(Jastreboff et al., NEJM, 2022) The 2025 head-to-head SURMOUNT-5 trial confirmed tirzepatide's superior metabolic effect across multiple endpoints in non-diabetic patients with obesity

Liposomal or intravenous formulations may improve absorption, but clinical evidence in liver health remains limited
