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Mar 2023;237(3):e13913
Thimerosal induces apoptotic and fibrotic changes to kidney epithelial cells in vitro
Common topical formulations of lipid conjugates of Vit C include ascorbyl-6-palmitate, disodium isostearyl 2- O -ascorbyl phosphate and tetraisopalmitoyl ascorbic acid 18,19
In essence, radical reactions circumvent the spin barrier limiting triplet oxygen reactivity, thus driving thermodynamically favorable lipid oxidation, leading to the disruption of membrane integrity and function