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Indeed, enhanced levels of oxidant species within a cell can lead to permanent cellular damage and contribute to cell death (Redza-Dutordoir and Averill-Bates, 2016)

Gut stem cell aging is driven by mTORC1 via a p38 MAPK-p53 pathway
Rengan, R., Mitra, N., Liao, K., Armstrong, K

A.AllenM.et al (2008)
